Immature Astroglia Track Fluid-Intelligence Decline in Epilepsy Patients
An observational study of people with mesial temporal lobe epilepsy found that more pathological immature astroglia in the hippocampus was ...
Tag: dentate gyrus
One Synapse, Many Memories: How the Brain Builds LTP in Different Ways
New evidence shows the hippocampus expresses multiple mechanistically distinct forms of long-term potentiation, shaped by sex, brain region, and induction ...
A Hidden Brain Enzyme Emerges as the Secret Weapon Against Memory Decline in Aging
Scientists have discovered that an aging-induced secreted phospholipase called PLA2G2F acts as a neuron-derived signal that protects synapses, calms inflammatory ...
New Protocol Keeps Living Brain Slices Alive for Weeks to Track Birth of New Neurons
Researchers have refined a decades-old method for keeping intact mouse hippocampal slices alive for weeks, enabling precise quantification of newborn ...
Brain Cells Can Be Reversed to Immaturity by Seizure-Like Activity Only After a Developmental Switch
A new mouse study shows that electroconvulsive treatment can drive hippocampal neurons back to an immature state only from about ...
New spatial sequencing method maps RNA turnover kinetics across the mouse brain
Spatial NT-seq combines metabolic RNA labeling with in situ chemical recoding to co-map newly synthesized and pre-existing RNAs, revealing the ...
Stem Cell Enzyme PLA2G7 Emerges as a Driver of Age-Related Memory Decline
Researchers report that suppressing the lipid-metabolizing enzyme PLA2G7 in hippocampal neural stem cells restores inhibitory synapses and improves memory in ...
Aging Brains Respond Differently in Males and Females, Mouse Study Reveals
A new study in accelerated-aging mice shows that a neurogenesis-boosting compound rescues memory and hippocampal plasticity in males but not ...
Single-Cell Map Reveals How the Epileptic Brain Rewires Its Connections
A single-nucleus RNA-seq atlas of the epileptic mouse hippocampus reveals that each cell type and subfield mounts its own distinct ...
How the Brain Tunes Inhibition to Balance Memory Flexibility and Stability
Researchers at the Institute for Neurosciences CSIC-UMH show that inhibitory activity in the dentate gyrus dynamically shifts the hippocampus between ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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