Blood Pressure Drug Boosts Cancer Medication Levels in Rat Study, Raising Interaction Concerns
A rat study found that the anticancer drug anlotinib substantially increases blood levels of the antihypertensive amlodipine, raising safety concerns ...
Tag: cytochrome P450
Pyrethroid Resistance and Low Awareness Thwart Lymphatic Filariasis Elimination in Nigeria
A One Health study in Sokoto State, Nigeria, finds low lymphatic filariasis awareness, near-total pyrethroid resistance in mosquitoes, and molecular ...
Turkey Tail Fungus Rewires Its Genes to Survive Toxic Biofuel Wastewater
Researchers show that the white-rot fungus Trametes versicolor switches on a universal genetic stress program to detoxify toxic hydrothermal liquefaction ...
Endophytic Fungus Transforms Tree Diterpene Into Potent Antiparasitic Compounds
An endophytic fungus isolated from cypress leaves selectively epoxidizes a plant diterpene using a P450-like enzyme, yielding two novel compounds ...
Fish Enzymes That Detoxify Pollutants May Also Turn Toxins Against Them
A comprehensive review reveals how cytochrome P450 enzymes in fish simultaneously detoxify aquatic pollutants and regulate hormones, making them powerful ...
Flavonoid Diosmetin Targets Endothelial Enzyme to Rewire Lung Cancer Immune Defenses
New research identifies endothelial CYP3A5 as a functional vulnerability in lung adenocarcinoma and shows that the natural flavonoid diosmetin suppresses ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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