Tag: cytochrome P450

A 2026 perspective proposes that large language models could integrate genetic and clinical records to identify possible pharmacogenomic phenoconversion, while ...

In vitro experiments show juglone, a naphthoquinone from walnut green husks, potently and competitively inhibits the human drug-metabolizing enzyme CYP2C9, ...

A new study in Cell Death Discovery shows that the conserved mitochondrial protein Mppa maintains the Drosophila testis stem cell ...

An integrated transcriptomic and metabolomic study of Sophora moorcroftiana has prioritized candidate enzyme families and regulatory genes underlying quinolizidine alkaloid ...

A new multimodal transformer-CNN model called InfoMedex predicts 168 types of drug-drug interactions from molecular structure and uses atom-level attribution ...

An integrated multi-omics study identifies the cytochrome P450 enzymes CYP1A1 and CYP1B1 as potential drivers and biomarkers of smoking-related lung ...

A new review argues that cytochrome P450 inhibition, long treated as a drug-discovery liability, can be a powerful therapeutic strategy ...

A Rwandan policy brief argues that genomic surveillance of Anopheles gambiae resistance is essential to guide cost-effective, site-specific insecticide deployment ...

A retrospective study of 19 children with blood cancers suggests topiramate may offer a well-tolerated maintenance antiseizure option during chemotherapy ...

Japanese researchers have established the first stable genetic transformation system for the multiple-herbicide-resistant weed Echinochloa phyllopogon using particle bombardment, creating ...