Hidden Chemical Tags on Proteins and RNA Team Up to Drive Inflammatory Bowel Disease
A new review in the Journal of Translational Medicine details how chemical tags on proteins and RNA interact to control ...
Tag: Crohn’s disease
How Autophagy’s Dual Role Shapes Inflammatory Bowel Disease
A sweeping new review maps how canonical, selective, and non-autophagic functions of autophagy genes jointly determine the course of inflammatory ...
Machine Learning Framework Distills Crohn’s Disease Risk From Half a Million Genetic Variants
A hybrid XGBoost-based machine learning framework has distilled Crohn's disease risk prediction down to just 15 genetic variants, achieving over ...
When Crohn’s Stomas Become Permanent: 40-Year Study Tracks Long-Term Outcomes in 422 Patients
A 43-year cohort study of 422 Crohn's disease patients shows that 87 percent of stomas created for anorectal disease ultimately ...
Stem Cell Therapy Eases Crohn’s Disease by Blocking Iron-Driven Cell Death
New research shows mesenchymal stem cells relieve Crohn's disease in mice by upregulating the enzyme CBS, restoring antioxidant defenses and ...
CRISPRi Screens Inside Living Mice Map How E. coli Adapts to the Gut
An in vivo CRISPR interference platform reveals the diet-dependent, strain-specific and inflammation-shaped genetic adaptations that allow different Escherichia coli strains ...
Gut Enzyme LRRK2 Rises in Crohn’s Disease but Not in Parkinson’s or REM Sleep Disorder
A French study finds colonic LRRK2 expression is strongly increased in Crohn's disease but not elevated in Parkinson's disease or ...
Fatal Fungus Masquerading as Crohn’s Disease and Tuberculosis Kills Young Man
A fatal case of disseminated histoplasmosis in an immunocompetent young man highlights how the fungus can mimic intestinal tuberculosis and ...
Environment, Not Just Genes: Exposome Framework Targets Inflammatory Bowel Disease Prevention
A new Perspective in Nature Reviews Gastroenterology & Hepatology proposes an exposome-based framework to prevent inflammatory bowel disease through targeted ...
Epigenetic changes in stromal cells drive disease-promoting tissue niches in Crohn’s disease
Crohn’s disease is often described as an immune disorder, but a new study suggests that the cells forming the body’s ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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