Mouse Studies Map the Broad Immunomodulatory Reach of Bacterial Lysates
A systematic review of 34 murine studies published from 2010 to 2025 finds bacterial lysates show consistent preclinical immunomodulatory effects ...
Tag: colitis
Vimentin neutralizing antibody ameliorate inflammatory bowel disease by inhibiting fibrosis and inflammatory cell death
An anti-vimentin antibody reduced fibrosis, inflammatory and necroptotic markers in DSS-treated mice and lowered fibrosis-related factors in cultured human colon ...
Dual-Origin Probiotic Blend Eases Gut Inflammation in Rat Colitis Model
A formulation combining a plant-derived Lactobacillus plantarum strain with a human-derived Lactobacillus fermentum strain reduced inflammation biomarkers and showed no ...
TIMD4-targeted nanoparticles reduce colitis inflammation in mice
A macrophage-targeted TIMD4 peptide nanoparticle reduced inflammation and monocyte recruitment in a mouse colitis model without establishing clinical benefit in ...
Banana Starch Nanoparticles Worsen Colitis in Mice, While Native Starch Helps
A new mouse study shows banana starch nanoparticles worsen colitis by damaging tight junctions and disrupting gut microbes, while native ...
Surface Y RNAs Turn Monocytes into Inflammatory Amplifiers
Researchers report that Y RNAs on the surface of human monocytes bind extracellular histones and amplify TLR2/TLR4-driven inflammatory signaling, with ...
Low fecal elastase in immunotherapy diarrhea may reflect dilution, not pancreatic insufficiency
A retrospective study of 388 patients suggests that low fecal elastase in immune checkpoint inhibitor-related diarrhea is more likely a ...
REV-ERBβ emerges as a non-redundant brake on TH17-driven inflammation
New research reveals that the circadian nuclear receptor REV-ERBβ acts as a distinct, non-redundant negative regulator of pro-inflammatory TH17 cell ...
Can the Food You Eat Rewire Your Genes? The MicroRNA Controversy Dividing Scientists
A comprehensive new review finds that food-derived microRNAs can survive digestion and locally influence gut inflammation and microbiota, but claims ...
Engineered Probiotic Turns Gut Bacteria Into Living Drug Factories to Shield the Liver From Colitis Damage
Scientists engineered a probiotic bacterium that produces the anti-inflammatory lipid palmitoylethanolamide directly in the gut, protecting mice with chronic colitis ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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