Two Master Genes That Decide Whether Blood Cells Are Born or Turn Cancerous
A new review details how the Runx1 and Gata2 transcription factors architect the epigenetic landscape of blood formation and how ...
Tag: chromatin
Epigenetics Beyond the Clinic: A New Journal Charts the Field’s Next Frontier
The launch of the open access journal Epigenetics Communications marks a push to understand dynamic epigenetic networks, publish negative results ...
Sperm’s Epigenetic Balancing Act: Flexibility Versus Stability in the Male Germline
A new review in Cellular and Molecular Life Sciences maps how the epigenome of the postnatal male germline balances the ...
Aging and Rejuvenation Converge on the Same Epigenetic Switch in Mouse Skin
Whole-genome sequencing of mouse skin shows that aging and partial reprogramming converge on PRC2 target genes, where methylation entropy rises ...
Phase-Separation Discovery Reveals How a Key Gene-Regulating Complex Assembles Itself
New research shows that the scaffolding protein KANSL1 forms liquid-like condensates that assemble the NSL chromatin complex and drive the ...
Epigenetic Switches That Drive MYC Gene Amplification in Aggressive Cancers
Fox Chase Cancer Center researchers have discovered that MYC gene amplification in cancer is driven by a regulated epigenetic program ...
AI Agent Learns Expert Rules for Chromatin Data Analysis
A new Genome Biology study introduces ChromSkills, a curated library of expert-encoded Skills that makes AI agents consistent, stable and ...
Histone Chaperone NAP1L1 Keeps Gene Expression Steady in Stem Cells
A systematic screen combining single-cell RNA sequencing with ChIP-seq data has identified the histone chaperone NAP1L1 as a stabilizer of ...
Hibernating Hamsters Rewrite Their Histones, Not Their DNA, to Survive Winter
A new study of Syrian hamster liver shows that facultative hibernation is accompanied by dynamic changes in histone lysine acetylation ...
Histone readers MLLT1 and MLLT3 concentrate AID to confer locus specificity
New research in Nature shows that the histone readers MLLT1 and MLLT3 license the antibody-mutating enzyme AID at specific genomic ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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