xDecoder Pushes Genomic Foundation Models Toward Personal Gene Expression Prediction
A new decoding framework called xDecoder more than triples few-shot accuracy of genomic foundation models for personal gene expression prediction ...
Tag: Chromatin Accessibility
Ancient DNA Word Vocabularies Govern How Cell Types Evolve Across Species
Deep-learning analysis of single-nucleus multi-omic data from flatworms and vertebrates reveals that conserved motif vocabularies maintain cell type family identities ...
Single-cell maps reveal how enhancers regulate their target genes
Genomic dark matter has long been the paradox at the heart of human genetics. The vast majority of disease-associated DNA ...
Two Ways to Read a Cell’s Master Switches Reveal Hidden Biases in Gene Regulation Studies
A systematic comparison shows that ATAC-seq and multiplexed reporter assays capture distinct, complementary aspects of transcription factor activity, with each ...
Two Tests Could Sharpen Transcription Factor Footprints in V-Plots
Researchers propose using V-channel width and inside-V enrichment to distinguish genuine transcription-factor footprints from enzyme-generated artifacts in chromatin-accessibility data.
Unveiling the Invisible: Innovative Technique Exposes ‘Hyperaccessible’ Regions in Newly Replicated DNA
In a groundbreaking study published in the journal “Cell,” researchers from the Gladstone Institutes in San Francisco have unveiled transformative ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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