Tag: Chromatin Accessibility

Engineered genomic attachment sites dramatically increase the efficiency of site-specific DNA integration in both plant and human cells.

A new decoding framework called xDecoder more than triples few-shot accuracy of genomic foundation models for personal gene expression prediction ...

Deep-learning analysis of single-nucleus multi-omic data from flatworms and vertebrates reveals that conserved motif vocabularies maintain cell type family identities ...

Genomic dark matter has long been the paradox at the heart of human genetics. The vast majority of disease-associated DNA ...

A systematic comparison shows that ATAC-seq and multiplexed reporter assays capture distinct, complementary aspects of transcription factor activity, with each ...

Researchers propose using V-channel width and inside-V enrichment to distinguish genuine transcription-factor footprints from enzyme-generated artifacts in chromatin-accessibility data.

In a groundbreaking study published in the journal “Cell,” researchers from the Gladstone Institutes in San Francisco have unveiled transformative ...