Researchers have identified a METTL3/IGF2BP1-USP16-FUBP1-LDHA regulatory axis that drives glycolysis-dependent progression and gemcitabine resistance in pancreatic ductal adenocarcinoma, highlighting USP16 ...
New research shows that the TGF-β2 signaling molecule steers metastatic colon cancer cells toward autophagy-mediated resistance to the chemotherapy drug ...
A new systematic review finds that mutations, methylation, and expression loss of the ATM DNA repair gene are recurrent and ...
New research shows that the mitochondrial enzyme GDH1 sustains drug-tolerant persister cells in triple-negative breast cancer by coordinating glutamine metabolism, ...
A sweeping integrated genomics study reveals that chemotherapy-resistant tumors across multiple cancer types share a hyperproliferative, MYC-driven state, identifying the ...
A new review explains how small-cell lung cancer cells exploit lineage infidelity to switch molecular identities under therapy, and how ...
A new review in Cancer Cell International details how the tumor suppressor RUNX3 regulates apoptosis, drug efflux, cell cycle control, ...
Researchers report that the RNA-binding protein IGF2BP3 stabilizes m6A-tagged CENPA mRNA to fuel paclitaxel resistance in bladder urothelial carcinoma, identifying ...
New research shows the protein ECT2 drives papillary thyroid carcinoma growth by suppressing lipoic acid metabolism, activating PI3K/AKT signaling and ...
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