Enzyme GDH1 Keeps Breast Cancer Persister Cells Alive During Chemotherapy
New research shows that the mitochondrial enzyme GDH1 sustains drug-tolerant persister cells in triple-negative breast cancer by coordinating glutamine metabolism, ...
Tag: chemoresistance
Cancer Cells Defy Quiescence Doctrine as MYC Drives a Proliferative Chemoresistance Program
A sweeping integrated genomics study reveals that chemotherapy-resistant tumors across multiple cancer types share a hyperproliferative, MYC-driven state, identifying the ...
Shifting Identities: How Lung Cancer Cells Change Face to Outsmart Treatment
A new review explains how small-cell lung cancer cells exploit lineage infidelity to switch molecular identities under therapy, and how ...
RUNX3 Emerges as a Master Switch Behind Cancer Chemoresistance
A new review in Cancer Cell International details how the tumor suppressor RUNX3 regulates apoptosis, drug efflux, cell cycle control, ...
Hidden RNA Tag Drives Paclitaxel Resistance in Bladder Cancer, Study Finds
Researchers report that the RNA-binding protein IGF2BP3 stabilizes m6A-tagged CENPA mRNA to fuel paclitaxel resistance in bladder urothelial carcinoma, identifying ...
Thyroid Cancer Protein Rewires Tumor Metabolism and Drives Drug Resistance
New research shows the protein ECT2 drives papillary thyroid carcinoma growth by suppressing lipoic acid metabolism, activating PI3K/AKT signaling and ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!