Tag: Cellular senescence

A new review in Cancer Reports details how the senescence-associated secretory phenotype can both suppress and fuel tumors, and how ...

New research reveals that the deubiquitinase USP22 protects bone marrow stem cells from oxidative stress-induced senescence by stabilizing the transcription ...

A comprehensive new review details how senescent fibroblasts, macrophages, keratinocytes and stem cells drive skin aging through ROS, DNA damage, ...

Researchers have identified the little-studied transmembrane protein PTCHD4 as a novel regulator of cellular senescence whose deletion extends lifespan and ...

A new review in Biogerontology argues that senescent cells and their inflammatory secretions act as a convergent, independently targetable driver ...

Researchers have introduced RamanOmics, a label-free strategy combining Raman imaging with spatial and single-cell transcriptomics to map a lipid-linked vibrational ...

A new RamanOmics platform combines Raman chemical imaging with spatial transcriptomics to reveal the biochemical remodeling that defines senescent cells.

A new review argues that neurons can acquire senescence-like states in aging and neurodegenerative disease, but peripheral senescence markers cannot ...

New research in mice shows that cannabidiol reduces cardiac fibrosis and diastolic dysfunction in HFpEF by clearing senescent cells, suppressing ...

New research identifies the cholesterol synthesis enzyme DHCR24 as a driver of endometrial carcinoma progression and a potential prognostic biomarker ...