Repeated Infections May Speed Up Biological Aging, Large Chinese Cohort Study Finds
A prospective cohort study of 7,614 Chinese adults links frequent and severe infection trajectories to accelerated biological aging and higher ...
Tag: Cellular senescence
Aging Eye Study Uncovers Molecular Cascade Behind Blinding Retinal Scarring
Researchers have identified a LAPTM5-WWP2-OPTN mitophagy cascade that drives retinal pigment epithelium senescence and subretinal fibrosis through cGAS-STING activation, with ...
Better Survival in Mice Is Not Proof of Senolytic Anti-Ageing Success, Researchers Warn
A new letter in the Journal of Translational Medicine argues that a senolytic vaccine study showed real therapeutic benefit in ...
Cellular Senescence Takes Center Stage as ICSA Gathers Global Aging Researchers in Seoul
The journal Aging will support the 11th International Cell Senescence Association Conference, taking place November 3 to 5, 2026, at ...
Stressed Cells Hold On to Their Color: ER Stress Links Senescence to Stubborn Age Spots
New research shows that chronic IRE1α-mediated endoplasmic reticulum stress simultaneously boosts melanin production and impairs pigment clearance, explaining why solar ...
Shikonin Shields the Heart From Chemotherapy Damage by Restoring Mitochondrial Balance
A new study in rats and cardiac cells shows that the natural naphthoquinone shikonin protects the heart from doxorubicin chemotherapy ...
Feverfew Compound Parthenolide Eases Skin Fibrosis by Stabilizing Mitochondria-ER Contacts
A new study shows that parthenolide, a compound from feverfew, alleviates cellular senescence and skin fibrosis in localized scleroderma by ...
Stem cell rejuvenation pathway points to new periodontal bone repair strategy
Researchers at Sichuan University found that restoring the protein IGFBP5 reverses senescence in dental follicle stem cells via WNT5B signaling, ...
Aging Muscle Fails Through Broken Cell-to-Cell Communication, Review Finds
A new review in Aging Cell argues that skeletal muscle aging is driven by the breakdown of multicellular communication networks ...
Leaking Mitochondrial DNA Emerges as a Central Engine of Cellular Aging
A new review in Biogerontology argues that leaking mitochondrial DNA activates the cGAS-STING innate immune pathway in senescent cells, sustaining ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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