Magnesium Sulfate Shows Neuroprotective Effects in Mouse Model of Postoperative Cognitive Dysfunction
A new experimental study links magnesium sulfate's neuroprotective effects to AMPK/PINK1/Parkin signaling in postoperative cognitive dysfunction.
Tag: cellular energy metabolism
Patient-derived cells reveal metabolic and lysosomal defects in TFE3 neurodevelopmental disorder
Patient-derived fibroblasts with TFE3-associated neurodevelopmental disorder showed metabolic rigidity, dysfunctional lysosomes, impaired migration and an unstable extracellular-matrix interface.
SIRT2: The NAD-Dependent Enzyme That Ties Metabolism to Aging
A new review highlights how the NAD+-dependent deacetylase SIRT2 regulates glucose, lipid, and mitochondrial metabolism while influencing inflammation, genome stability, ...
CoQ10 Fails to Deliver a Performance Edge for Athletes, Major Meta-Analysis Finds
A systematic review and meta-analysis of 24 randomized trials finds that coenzyme Q10 supplementation shows no robust overall benefit for ...
Regulating PGC-1α: interactions, modifications, and drug targeting approaches
The master metabolic conductor PGC-1α, long recognized as the central transcriptional coactivator governing cellular energy metabolism across heart, skeletal muscle, ...
Human TOM and TIM22 complexes join forces to import mitochondrial carriers
For the first time, scientists have captured the human machinery that imports metabolite carriers into mitochondria in the act of ...
Scientists Reveal How Cells Harness Isolated ‘Powerhouses’ to Restore Energy Function
Mitochondria, often described as the cell’s powerhouses, perform an essential role far beyond mere energy production. These intricate organelles generate ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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