Oral Drug S-1 Linked to Longer Survival Than Capecitabine in Metastatic Breast Cancer Study
A retrospective cohort study of 123 patients suggests the oral fluoropyrimidine S-1 may deliver longer overall survival than capecitabine as ...
Tag: CDK4/6 inhibitors
Oncologist Dennis Slamon Wins 2026 Albany Prize for Targeted Breast Cancer Breakthroughs
UCLA oncologist Dr. Dennis Slamon has received the 2026 Albany Prize for discoveries that identified HER2-positive breast cancer and produced ...
Phase III Trial Tests Blood-Based MRD Monitoring to Spare Breast Cancer Patients CDK4/6 Inhibitor Toxicity
The new global phase III AFT-70 NAVIGATE trial will test whether ultrasensitive Signatera MRD blood monitoring can safely guide CDK4/6 ...
Hormone Receptor Levels Predict Who Benefits Most from Standard Advanced Breast Cancer Therapy
The largest real-world study of its kind shows that quantitative oestrogen and progesterone receptor levels, measured in recent tumour biopsies, ...
Oral Giredestrant Combination Nearly Doubles Survival Without Progression in Metastatic Breast Cancer
The phase 3 evERA study found that an all-oral combination of the next-generation estrogen receptor degrader giredestrant and everolimus significantly ...
Less Surgery, Smarter Drugs: The Trials Rewriting Breast Cancer Care in 2025
Landmark trials from 2024 and 2025 are transforming breast cancer care by safely scaling back surgery while unleashing antibody-drug conjugates, ...
Hidden Nuclear Role of Metabolic Enzyme FAH Drives Breast Cancer Drug Resistance
Boston Children's Hospital researchers discovered that the metabolic enzyme FAH moves into the nucleus of breast cancer cells and drives ...
Chemotherapy After Hormone Therapy Fails Leaves Metastatic Breast Cancer Patients With Grim Odds
A study of more than 5,000 US patients with HR-positive/HER2-negative metastatic breast cancer found median survival of only 13.5 months ...
Hidden ESR1 Mutations Signal Trouble Before Breast Cancer Progresses
A large U.S. real-world study found that ESR1 mutations emerging during first-line therapy for ER-positive metastatic breast cancer are linked ...
Biomarkers Predict Response to Palbociclib-Anastrozole Therapy
In an intense and promising leap forward in the fight against breast cancer, researchers have unveiled groundbreaking findings on the ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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