Fibroblast Protein GNL3 Emerges as Hidden Culprit in Chemotherapy Heart Damage
New research in mice shows that the nucleolar protein GNL3, produced by cardiac fibroblasts, worsens doxorubicin-induced heart injury by driving ...
Tag: cardiac fibroblasts
Stem Cell Screening Platform Hunts for Drugs to Halt Cardiac Fibrosis
Stanford researchers have published a protocol for a high-throughput stem cell-based screening platform that identifies potential antifibrotic compounds for cardiac ...
ParTIpy Brings Pareto Task Inference to Million-Cell Single-Cell Datasets
An open-source Python package called ParTIpy scales archetypal analysis and Pareto task inference to millions of single cells, offering a ...
Loss of a Single Splicing Protein Reshapes the Heart’s Scarring Response
Deleting the RNA splicing factor PTBP1 in cardiac fibroblasts reshapes the profibrotic response by altering alternative splicing of key fibrosis-related ...
Scientists propose new blueprint to model and reverse atrial fibrosis in AF
A new review proposes a staged, evidence-bound framework combining patient-specific iPSCs, atrial microphysiological systems and nanomedicine to model and potentially ...
New study maps diverse cardiac fibroblasts driving HFpEF, revealing therapeutic targets
Heart failure with preserved ejection fraction, or HFpEF, has become one of cardiology’s most difficult challenges. Patients retain a seemingly ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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