Tag: CAR T cells

A new review traces how CRISPR genome editing has evolved from blunt molecular scissors into increasingly precise therapeutic tools for ...

Researchers have developed fourth-generation CAR T cells targeting mucin 1 that show superior proliferation, reduced exhaustion, and enhanced tumor-killing activity ...

Researchers report that the membrane protein TSPAN32 enhances CAR-T cell potency by assembling the IL-2 receptor complex and amplifying intracellular ...

An armoured GPC3-targeted CAR T cell therapy engineered to resist TGFβ-mediated immunosuppression showed promising initial results in 36 patients with ...

A systematic review of 75 studies maps how organoids, spheroids, tissue slices, and tumor-on-a-chip systems are being used to test ...

Researchers propose reframing drug development as an iterative, data-centric learning system in which single-cell readouts from human immunotherapy responses continuously ...

A new study in Nature Biomedical Engineering combines AI-designed protein binders with CAR engineering to define the sequence and structural ...

A new review details how triboelectric nanogenerators that harvest the body's own mechanical energy could power cancer detection, drug delivery ...

A comprehensive review finds that patient-derived tumor organoid co-culture with immune cells offers the most physiologically faithful platform yet for ...