Suppressor tRNAs restore mutant p53 and shrink tumours in mice
Suppressor tRNAs restored full-length p53 from nonsense-mutant TP53 and, delivered via lipid nanoparticles, cut tumour volume by up to 74 ...
Tag: cancer
Bile duct microbiome differs in structure between benign and malignant obstruction
Shotgun sequencing of bile from 48 patients found similar microbial diversity in benign and malignant bile duct obstruction, but different ...
NCI Website Spreads Proven Cancer Control Programs into Primary Care
The National Cancer Institute's EBCCP website disseminates 79 evidence-based interventions tested in clinical settings such as primary care.
Polyamines emerge as metabolic controllers of RNA modifications and translation
A new mini review in Amino Acids argues that polyamines may regulate RNA modifications, hypusination and translation, linking cellular metabolism ...
Exosomes, mitochondrial vesicles and microRNA cargo emerge as a new chemopreventive frontier in cancer
A new review in Genes & Nutrition proposes that exosomes, mitochondria-derived vesicles and their microRNA cargo form a programmable signaling ...
Hydroxychloroquine Fails to Boost Chemotherapy Response in Pooled Cancer Trial Analysis
A systematic review and meta-analysis of seven studies in 383 patients found that adding hydroxychloroquine to standard chemotherapy did not ...
AI and molecular studies converge to decode cancer complexity in new research collection
A new Frontiers in Oncology editorial surveys thirteen studies using artificial intelligence and molecular data to advance cancer diagnosis, prognosis ...
New website offers evidence-based support for carers of people with severe breathlessness
Researchers co-developed a free, nationally endorsed website covering six carer-identified topics to support unpaid and family carers of people with ...
Cancer Stigma Follows Survivors Long After Treatment Ends, Review Finds
A Flinders University scoping review of more than 100 studies finds that cancer-related discrimination affects employment, insurance, healthcare and social ...
Silymarin Shows Modest Liver-Protective Effects in Chemotherapy Patients, Meta-Analysis Finds
A meta-analysis of six randomized trials found silymarin significantly lowered AST and ALT in chemotherapy patients, with no significant effect ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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