Scientists Cut Ovarian Cancer’s Glutamine Fuel Line by Blocking a Single RNA Switch
Researchers in China have identified a long non-coding RNA, SLC39A13-AS1, that drives glutamine addiction in ovarian cancer and shown that ...
Tag: cancer metabolism
Enzyme USP16 Drives Pancreatic Cancer Growth and Gemcitabine Resistance Through a Glycolytic Switch
Researchers have identified a METTL3/IGF2BP1-USP16-FUBP1-LDHA regulatory axis that drives glycolysis-dependent progression and gemcitabine resistance in pancreatic ductal adenocarcinoma, highlighting USP16 ...
New spatial metabolomics method maps hidden metabolic regions inside liver tumors
A new spatially guided metabolomics approach maps overlapping metabolic regions in liver tumors and reveals that over half of bulk-detected ...
Mushroom Compound Pachymic Acid Supercharges Lenvatinib Against Liver Cancer by Starving Tumors of Sugar
A new study shows that pachymic acid, a compound from the medicinal mushroom Poria cocos, synergizes with lenvatinib against hepatocellular ...
Lactate-Fueled Tumor Neighborhoods: Glycolysis Hotspots Recruit Neutrophils in Lung Cancer
A multi-omics study maps lactate-glycolysis activity in lung adenocarcinoma to fibroblasts and neutrophils, revealing spatially organized metabolic niches linked to ...
Ketogenic Diet May Prime the Body to Fight Cancer by Rewiring Metabolism and Immunity
A new review argues that the ketogenic diet may act as a systems-level sensitization platform in cancer therapy by simultaneously ...
Plasma-Treated Medium Strikes Ovarian Cancer Cells Through DNA Damage and Mitochondrial Collapse
German researchers report that plasma treated medium loaded with long-lived reactive species kills ovarian cancer cells by inducing DNA damage, ...
Starvation on a Petri Dish: How Fasting Rewires Cancer Cells and Exposes Their Weaknesses
A systematic review of eleven in vitro studies finds that fasting conditions consistently suppress IGF-1 and PI3K/AKT/mTOR signaling, inhibit glycolysis, ...
Fluorescent Probes Let Scientists Watch Glucose Move Through Living Animals in Real Time
University of Bath researchers have created fluorescent boronic acid probes that, combined with multiphoton FLIM imaging, can track glucose changes ...
Blood Fats May Fuel Lung Cancer Spread Through a Hidden Metabolic Switch
New research reveals that elevated triglycerides drive lung cancer metastasis through a lipid beta-oxidation and RhoA-dependent cytoskeletal pathway that tumour ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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