Tag: cancer immunotherapy

A new review in Molecular Cancer details how loss of the immune synapse molecule CD58 drives tumor immune evasion and ...

New research shows that fibrinogen-like protein 1 is overexpressed in endometrial adenocarcinoma and drives tumor growth, migration and invasion by ...

A new review traces how CRISPR genome editing has evolved from blunt molecular scissors into increasingly precise therapeutic tools for ...

Researchers have developed fourth-generation CAR T cells targeting mucin 1 that show superior proliferation, reduced exhaustion, and enhanced tumor-killing activity ...

A new review details how mRNA therapeutics are expanding beyond infectious disease vaccines into cancer immunotherapy, protein replacement, autoimmune tolerance, ...

Researchers engineered a fusogenic oncolytic vaccinia virus that displays IL-15Rα on infected tumor cells to locally trans-present IL-15, reprogramming the ...

A prospective Chinese pediatric study found that brentuximab vedotin combined with risk-adapted chemoimmunotherapy achieved 100 percent overall survival and allowed ...

New research shows that circulating tumor cells shed migrasomes carrying tumor antigens that activate CD8-positive T cells through cross-presentation, restricting ...

Researchers have built a fully open-source KNIME machine-learning workflow that curates thousands of PD-L1 bioactivity records and reliably predicts inhibitor ...

A new review details how interleukin-2 both powers and undermines tumor-infiltrating lymphocyte therapy, and how engineered alternatives may finally break ...