Chemoradiotherapy May Unlock Immunotherapy in Hard-to-Treat Rectal Cancer
A new review argues that neoadjuvant chemoradiotherapy may induce immune checkpoint blockade responsiveness in mismatch repair-proficient rectal cancer, with sequential ...
Tag: Biomarkers
Alzheimer’s Disease Beyond Amyloid: What Atherosclerosis Teaches Us About Dementia Risk
A new perspective argues that Alzheimer's disease should be understood through the same multidimensional, risk-based lens that transformed atherosclerosis, with ...
The Body’s Missing Signals: How Interoception Breaks Down in Borderline Personality Disorder
A new study in Translational Psychiatry shows that people with borderline personality disorder display selective, dimension-specific impairments in interoception that ...
Where does the immune pressure go? New framework explains immunotherapy resistance
A new Molecular Cancer review proposes immune-pressure redistribution as a unifying framework explaining why patients resist PD-1/PD-L1 blockade and how ...
Liquid Biopsy Offers a Non-Invasive Path to Precision Treatment for Bladder Cancer
A new review in the Journal of Translational Medicine synthesizes a decade of evidence showing that liquid biopsy analytes such ...
Scientists Clash Over Free Water Imaging as a Marker of Parkinson’s Disease Progression
A published exchange in npj Parkinson's Disease highlights the methodological debate over whether free water imaging can reliably serve as ...
Blood Metabolites and AI Reach Over 80% Accuracy in Supporting Autism Diagnosis
A double-blind clinical trial found that metabolites from folate-dependent one-carbon metabolism and the transsulfuration pathway, analyzed with machine learning, predicted ...
New Single-Molecule Technique Reads Intact Tau Proteins at Unprecedented Scale
A new single-molecule technique called Iterative Mapping enables large-scale quantification of intact tau proteoforms in control samples, disease models, and ...
Hidden Protein Signals Decide Why Immunotherapy Fails in Gut Cancers
A new review maps how secreted protein circuits in gastrointestinal tumours govern immune recruitment, suppression and response to checkpoint immunotherapy.
Falling Levels of Immune Protein sCD30 in Spinal Fluid Track Huntington’s Disease Progression
A Swedish study confirms that the immune protein TNFRSF8 (sCD30) is halved in the cerebrospinal fluid of Huntington's disease gene ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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