Small Set of Genes Drives Most Bias Between 3′ and 5′ Single-Cell RNA Sequencing Protocols
A systematic analysis of matched 3-prime and 5-prime single-cell RNA sequencing data shows that protocol-dependent expression bias is confined to ...
Tag: batch correction
AI Models Mine Blood Gene Data to Uncover New ALS Biomarkers
A computational study combining RNA sequencing of blood samples with machine learning and rigorous batch correction has identified 18 candidate ...
CytoVI: Deep learning model unifies antibody-based single-cell data across platforms
Researchers have developed CytoVI, an open-source deep generative model that integrates, denoises and imputes antibody-based single-cell data from flow cytometry, ...
ResolVI cleans up noisy spatial transcriptomics data after segmentation goes wrong
A new probabilistic deep learning model called ResolVI corrects misassigned RNA molecules and batch effects in spatial transcriptomics data, sharpening ...
Open-Source R Pipeline Brings Reproducible Automation to Targeted Mass Spectrometry
Researchers have unveiled MStargetR, an open-source, containerised R workflow that unifies vendor file conversion, automated peak integration, auditable review, and ...
Graph Transformer Puts Rare Cell States on the Map in Single-Cell Data
A new heterogeneous graph transformer called scFormer connects cells through their most specific genes rather than their most similar neighbors, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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