Molecular Brake Found That Keeps Lipid-Scrambling Protein TMEM63B Switched Off
Researchers at Institute of Science Tokyo show that the C-terminal tail of TMEM63B, particularly the Leu776 residue, acts as an ...
Tag: autoinhibition
Cryo-EM Reveals How ATP Switches Off the Human NLRP6 Inflammasome
Cryo-EM structures of human NLRP6 in ATP-bound and unbound conformations reveal how ATP serves as an endogenous inhibitor of inflammasome ...
Autophagy Protein AMBRA1 Unlocks NLRP3 Inflammasome Activation
Researchers have discovered that the autophagy protein AMBRA1 directly binds and allosterically opens the autoinhibited NLRP3 inflammasome, revealing a new ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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