Why aging immune systems turn against the body: a two-step model of B cell autoreactivity
A new GeroScience review proposes that B cell-intrinsic aging relaxes immune tolerance while chronic inflammaging selectively expands autoreactive B cell ...
Tag: autoimmunity
Men and Women Rewire Immune Tolerance Differently During Cancer Immunotherapy Side Effects
A new transcriptomic study reveals that biological sex shapes how regulatory T cells reprogram during checkpoint inhibitor toxicities and autoimmune ...
Master Switch Silenced: Distant DNA Element Holds Human Regulatory T Cells on Their Anti-Inflammatory Path
Researchers have identified a distal IRF4 chromatin regulatory element as the genomic control point that permits inflammation-induced reprogramming of human ...
How the body keeps insulin-producing cells in check may shape future diabetes therapies
A new commentary explains how the tightly regulated, slowly renewing beta-cell mass of the pancreas creates critical therapeutic windows for ...
Common Lupus Gene Variant Boosts Antiviral Defenses at the Cost of Autoimmunity Risk
Researchers at Cincinnati Children's found that a common lupus-associated IRF7 haplotype strengthens antiviral interferon responses while raising the risk of ...
How the body’s natural recycling system may reduce inflammation
Leuven, Belgium — 28 July 2026 — Researchers from VIB and KU Leuven, working with international collaborators, report that disabling ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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