New Nanoscale Genome Mapping Tool Pinpoints Causal Autoimmunity Variants
An Oxford-developed single-allele chromatin mapping platform called MCCv identifies causal noncoding variants in autoimmune disease and reveals that a neo-CTCF ...
Tag: autoimmunity
Common Sweetener Sucralose Shows Surprising Ability to Calm Autoimmune Attacks in Vitiligo
New research shows the artificial sweetener sucralose slows autoimmune depigmentation in mice and suppresses human CD8+ T cell activity by ...
Interferon-Gamma Emerges as a Potential Hub Linking Inflammation to Fibrosis in Sjögren’s Lung Disease
A new review proposes that interferon-gamma acts as a regulatory hub connecting immune activation, inflammatory amplification, and fibrotic remodeling in ...
Large Database Study Finds Vitiligo Patients Face Higher Risk of Autoimmune Thyroid Disease
A large multi-center retrospective cohort study using a national database confirms that patients with vitiligo face an increased risk of ...
NIH Backs Bold Epigenetics Quest to Decode How Immune Cells Walk the Tightrope Between Defense and Disease
Van Andel Institute's Dr. Derek Janssens has received a nearly $4.6 million NIH New Innovator Award to develop tools that ...
Antibodies in Newborn Cord Blood Raise Questions but Rarely Signal Disease in First Year
A prospective cohort study of 171 newborns found that roughly 15 percent tested positive for antinuclear antibodies in cord blood, ...
Massive Eight-Country Trial Shows Childhood Type 1 Diabetes Screening Works Across Europe
The EDENT1FI consortium screened more than 140,000 children in eight European countries and showed that harmonised autoantibody screening for early-stage ...
Inside the Germinal Center: How T Follicular Helper Cell Subsets Shape Immunity in Health and Disease
A new review in the Journal of Molecular Medicine maps how heterogeneous follicular helper T cell subsets are regulated by ...
Why aging immune systems turn against the body: a two-step model of B cell autoreactivity
A new GeroScience review proposes that B cell-intrinsic aging relaxes immune tolerance while chronic inflammaging selectively expands autoreactive B cell ...
Men and Women Rewire Immune Tolerance Differently During Cancer Immunotherapy Side Effects
A new transcriptomic study reveals that biological sex shapes how regulatory T cells reprogram during checkpoint inhibitor toxicities and autoimmune ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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