Eczema Drug Restores Nails in Boy With Rare 19-Nail Dystrophy, Case Report Shows
A case report describes a seven-year-old boy with dystrophy of 19 nails and no eczema whose nails nearly normalized after ...
Tag: atopic dermatitis
Innate Lymphoid Cells Emerge as Master Regulators of Tissue Health and Allergic Disease
A new review argues that innate lymphoid cells act as central coordinators of barrier tissue homeostasis, and that their dysregulation ...
How Skin Cells and Nerves Conspire to Drive the Relentless Itch of Eczema
A new review maps how keratinocyte-derived cytokines, neuropeptides, and JAK-STAT signaling transform itch from a symptom of atopic dermatitis into ...
Inflammatory Caspases Drive IL-33 Release From Skin in Atopic Dermatitis
A new study shows caspase-1/11 is required for IL-33 release from keratinocytes in vivo, and deleting these inflammatory caspases markedly ...
One Drug, Three Organs: Dupilumab Calms a Child’s Atopic Dermatitis, Asthma and Eosinophilic Esophagitis
A 48-week case report describes how the IL-4/IL-13 blocker dupilumab improved atopic dermatitis, asthma and eosinophilic esophagitis in a seven-year-old ...
Topical Roflumilast: Why Route of Administration Rewrites the Safety Story
A new pharmacokinetic review explains why the safety warnings attached to topical roflumilast, drawn largely from its oral COPD formulation, ...
Targeted Biologics Show Promise for Severe Allergy in Rare Genetic Immune Disorders
A new systematic review of 172 patients finds that dupilumab, omalizumab, and JAK inhibitors can meaningfully control severe atopic disease ...
Dogs and owners in the same home recognize cockroach allergens differently
A One Health study of 68 owner-dog pairs in Taiwan reveals that cohabiting humans and dogs develop distinct IgE recognition ...
Rare Genetic Syndrome Case Shows Skin Drug Dupilumab Clears Stubborn Eczema
A genetically confirmed case of Costello syndrome shows that the biologic drug dupilumab resolved severe, treatment-refractory eczema within one month, ...
Lost Genetic Brakes Push Immune Cells Into an Interferon State Seen in Eczema Patients
Researchers in Tokyo engineered a tracking system for Foxp3-deficient regulatory T cells and found that combined loss of Foxp3 and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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