Preclinical experiments demonstrate that combining the Trop2-directed antibody-drug conjugate sacituzumab govitecan with TRAIL agonists produces synergistic, caspase-dependent apoptotic cell death ...
A review highlights how targeting Survivin in breast cancer requires overcoming delivery and resistance barriers through synergistic combination therapies.
An in vitro investigation shows that an oleandrigenin-derived androstane selectively suppresses prostate cancer cell proliferation and modulates androgen receptor signaling.
A new study in Scientific Reports shows that piracetam reduces lung damage caused by cyclophosphamide in rats by modulating inflammatory ...
A review indicates that exosome-mediated microRNA transfer regulates apoptotic signaling pathways and drives chemoresistance in ovarian cancer.
A new study reveals that SPTLC2 enhances radiosensitivity in esophageal cancer by triggering endoplasmic reticulum stress and apoptosis.
Artemisinin-loaded nanoparticles show synergistic effects with ciprofloxacin against resistant bacteria and induce cytotoxicity in gastric cancer cells.
A review in Pathology and Oncology Research details how cancer cells develop composite resistance to multiple regulated cell death pathways ...
A new study in Cell Death Discovery shows that MCP-1 promotes a T-cell-supportive phenotype in specific mesenchymal stem cell populations ...
A narrative minireview indicates that targeting selenoproteins and cellular redox balance may provide novel therapeutic strategies against acute myeloid leukemia.
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