PET tracer lights up ferroptosis to track liver cancer immunotherapy in real time
Researchers combined anti-PD-L1 immunotherapy with the PARP inhibitor Olaparib to trigger ferroptosis in liver cancer and used the SLC7A11-targeted PET ...
Tag: anti-PD-L1
Gum Disease Protein Mfa1 Supercharges Anti–PD-L1 Cancer Immunotherapy in Mice
A recombinant adhesion protein from the gum disease bacterium Porphyromonas gingivalis activates dendritic cells through TLR2 and boosts the anti-tumor ...
Oral Wnt-blocking pill plus lenvatinib shows promise in endometrial cancer after immunotherapy fails
A phase 1b/2 trial found that the oral CBP–β-catenin inhibitor E7386 combined with lenvatinib produced durable responses in advanced endometrial ...
Collagen Receptor CD49b Emerges as Key Switch That Lets Breast Tumors Hide From Immunotherapy
Blocking the collagen receptor integrin alpha-2 (CD49b) on breast cancer cells remodels the tumor immune microenvironment and synergizes with anti-PD-L1 ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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