Lab-Grown Retinas Mirror the Real Thing, but Their Metabolism Lags Behind
A new metabolomic study shows that mouse retinal organoids share 148 of 166 detected metabolites with native retina, yet reveal ...
Tag: amino-acid metabolism
Ebola Survivors With Lasting Illness Show Distinct Metabolic Fingerprints in Blood
Untargeted metabolomics of Ebola survivors in Sierra Leone reveals that those with post-Ebola syndrome show broad downregulation of TCA cycle, ...
Blood Metabolites Reveal a Prognostic Fingerprint for Cervical Cancer
A GC-MS metabolomics study of 55 cervical cancer patients has identified serum biomarkers linked to disease stage, treatment and prognosis, ...
Metabolic Shape-Shifters: How Breast Cancer Stem Cells Rewire Their Fuel to Survive and Spread
A new review in Cellular and Molecular Life Sciences details how breast cancer stem cells use flexible metabolic programs and ...
Seaweed in Fish Feed Rewires the Gut Microbiome to Boost Amino Acid Metabolism
A multi-omics study shows that supplementing grass carp feed with macroalgae, especially Sargassum hemiphyllum, enriches gut Shewanella bacteria that enhance ...
Hidden Fungal Allies Help Peas Survive Zinc-Starved Soils Through Whole-Plant Signaling
New research shows that the mycorrhizal fungus Rhizophagus irregularis helps pea plants tolerate zinc deficiency by boosting zinc uptake, restoring ...
Ancient Chinese Herbal Formula Reverses Muscle Wasting in Lung Cancer Mice
A classical Chinese herbal formula, Huangqi Guizhi Wuwu Decoction, reversed muscle wasting in lung cancer cachexia mice by restoring amino ...
Faulty RNA Splicing of SCARB1 Linked to Metabolic Collapse in Early Pregnancy Loss
A new study links dysregulated alternative splicing of the cholesterol receptor gene SCARB1, potentially controlled by the transcription factor TEAD4, ...
A Genetic Saboteur: Scientists Uncover Why Rice Surrenders to the Cold
Researchers have identified the rice transcription factor OsbHLH6 as a negative regulator that represses the cold-resilience gene OsMADS57 and disrupts ...
Too Much Cysteine Comes at a Cost: Surplus Amino Acid Triggers Deadly Iron Overload in Cells
A new Nature Metabolism study shows that excess free cysteine disrupts mitochondrial iron homeostasis and triggers a distinct iron-dependent cell ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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