Blood Cells From 80-Year-Olds Rejuvenated Into Brain Cells With Molecular Age Under 20
University of Bonn researchers directly reprogrammed red blood cell precursors from elderly donors into neural stem cells whose epigenetic clocks ...
Tag: Alzheimer’s disease
Autopsy Study Reveals Amyloid Plaques Explain Alzheimer’s Gene Risk But Not Women’s Tau Burden
A landmark autopsy study of 2,550 brains shows APOE-ε4 drives medial temporal tau through amyloid-β while women's tau burden persists ...
Multimodal AI in Mental Health Care Leans Heavily on a Single Dataset, Review Finds
A scoping review of 19 studies finds that multimodal AI fusing raw images with non-image data in mental and cognitive ...
The Golgi Apparatus Emerges as a Hidden Driver of Alzheimer’s Disease
A new review argues that the long-overlooked Golgi apparatus, supported by human genetic, proteomic, and lipidomic evidence, may be a ...
Two Separate Brain Gradients Reveal How Aging and Alzheimer’s Reshape Connectivity
A large two-cohort neuroimaging study shows that aging and Alzheimer's disease reorganize brain functional connectivity along two distinct cortical gradients, ...
Machine Learning Pinpoints ANKIB1 as a New Alzheimer’s Biomarker in Brain Insulating Cells
An integrated analysis of single-cell, bulk and spatial transcriptomic data identifies oligodendrocyte palmitoylation as a key dimension of Alzheimer's disease ...
Massive single-nucleus atlas reveals how genetic risk for brain disease acts cell by cell
A single-nucleus atlas of 5.6 million brain cells from 1,384 donors maps cell-type-specific genetic regulation underlying Alzheimer's disease, schizophrenia and ...
Ancient Chinese Formula Decoded: Machine Learning Reveals How Bushen-Yizhi May Fight Alzheimer’s
Researchers combined mass spectrometry, machine learning and animal experiments to reveal how the traditional Chinese formula Bushen-Yizhi protects against Alzheimer's-like ...
Four Key Risk Factors Drive Dementia Risk Among American Indians, Study Finds
An NIH-supported Boston University study of the Strong Heart Study cohort found that limited education, hypertension, social isolation, and depression ...
Dementia May Not Be a Brain Disease at All, NIH Scientists Argue
NIH researchers argue that dementia may be the late-life manifestation of a systemic failure of energy regulation rather than a ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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