AI Meets Living Cells in $28.6 Million Bid to Predict Protein Misfolding Before Disease Strikes
A Stowers Institute scientist will help lead a $28.6 million ARPA-H effort to generate billions of protein aggregation measurements and ...
Tag: ALS
ALS’s ‘Lateral Sclerosis’ Revealed as a Dying-Back Degeneration of Upper Motor Neuron Axons
A clinical-neuropathological study shows that the lateral sclerosis of ALS reflects a length-dependent dying-back degeneration of upper motor neuron axons, ...
Single Brain Implant Decodes Speech and Gestures Together in Paralysis
A single high-density ECoG implant allowed three paralyzed participants to decode attempted speech and gestures simultaneously, driving a personalized avatar ...
ERC Starting Grants Fund Frankfurt Projects on Global Finance and Cell Aging
Goethe University Frankfurt researchers Johannes Petry and Seda Koyuncu have each won an ERC Starting Grant worth up to 1.5 ...
Three Blood Biomarkers Together Predict ALS Progression and Survival, Study Finds
A longitudinal study of 100 ALS patients shows that combined serum levels of 4-HNE, LBP, and NfL discriminate rapid disease ...
Beyond ALS: Misfolded SOD1 Emerges as a Shared Player in Brain Disease
A sweeping review of human neuropathological evidence shows that misfolded SOD1, long tied to familial ALS, coexists with TDP-43, tau, ...
Clinical Risk Scores Cannot Stand In for Neurofilament Biomarkers in ALS Trials, Study Finds
A reanalysis of the MIROCALS trial shows that the TRICALS clinical risk score adds useful prognostic information in ALS but ...
Experimental Drug DNL343 Fails to Slow ALS Progression in Randomized Trial
A randomized clinical trial in JAMA Network Open found that 200 mg per day of DNL343, an eIF2B activator, did ...
Aging Brain Circuits May Drive Muscle Weakness, Mouse Study Finds
A new mouse study links hyperexcitable neurons in the aged motor cortex to muscle weakness, with cortical firing frequency statistically ...
Deep learning reads the genome to flag ALS risk in over 47,000 people
An internationally validated deep learning model trained on genomes from more than 47,000 people can distinguish ALS patients from controls ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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