AI Protein Models Guide Cheaper, Sharper Antibody Tests for Crop Viruses
Researchers used AlphaFold3 structure predictions to select viral coat protein epitopes, producing low-cost polyclonal antibodies with markedly better specificity for ...
Tag: AlphaFold3
A Single-Celled Parasite Carries More Rab Genes Than Humans, and AlphaFold3 Reveals Why
A computational study reveals that the parasitic amoeba Entamoeba histolytica encodes more than ninety Rab GTPase genes whose predicted structures ...
Hidden Fibroblast State at the Pancreatic Tumor Frontier Predicts Poor Survival and Points to Existing Drugs
Integrating single-cell and spatial transcriptomics, researchers identified a novel invasive-frontier fibroblast state and the multicellular community it defines, which independently ...
RPA Joins the Telomerase Team: New Complex Revealed in Fission Yeast
A new PLOS Genetics study shows that the single-stranded DNA-binding protein RPA forms an essential ternary complex with telomerase and ...
Histidine Clusters Reveal How Heat and pH Switch On the Sperm Channel CatSper
New research in PLOS Biology shows that evolutionarily tuned histidine clusters on the sperm channel CatSper act as temperature- and ...
Self-Rejecting Mustard Genes Mapped to Boost India’s Cooking Oil Independence
Researchers at IIT Gandhinagar and ICAR-DRMR have mapped the self-incompatibility genes in India's toria and yellow sarson mustard varieties, opening ...
Pooled AlphaFold3 screening maps a bacterium’s protein interactions 100 times faster
Researchers have devised a pooled AlphaFold3 screening strategy that cuts the number of computational jobs needed to map an entire ...
Parasite Adhesion Receptor Emerges as Drug Target in Schistosomiasis Study
Computational structural analysis of Schistosoma mansoni integrins identifies the Smα1/Smβ1 heterodimer as a plausible RGD-recognizing receptor, offering a new experimentally ...
Hidden Protein From Circular RNA Shields Colon Cancer Cells From Fiery Death
A circular RNA derived from the PIAS1 gene encodes a previously unknown 108-amino-acid protein that colon cancer cells use to ...
Targeted Gene Sequencing Transforms Molecular Diagnosis of Hereditary Hemochromatosis
A Greek study shows that targeted next-generation sequencing combined with structural protein modeling improves the molecular diagnosis of hereditary hemochromatosis.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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