Salmonella’s SopB protein makes a key signalling lipid without host kinases
A new review explains how the bacterial effector SopB uses phosphatase, phosphotransferase and scaffolding activities to rewire host phosphoinositide signalling ...
Tag: Akt signalling
Annexin A6 emerges as a hidden switch controlling leukaemia cell survival and drug response
New research reveals that the membrane protein Annexin A6 regulates apoptotic priming and BCL-2 dependency in acute lymphoblastic leukaemia, with ...
How Nutrient Availability Rewires Mitochondria and Cytoskeleton in 3D Lung Cancer Models
A new systems-level study in 3D lung adenocarcinoma models shows that nutrient availability drives tumour cells into two distinct mitochondrial ...
Immune Checkpoint VISTA Doubles as a Growth Engine Inside Mesothelioma Cells
New research shows the immune checkpoint molecule VISTA also drives proliferation within mesothelioma cells through RIPK1-associated and AKT-dependent signalling, making ...
Blocking Myostatin Rebuilds Wasted Muscle in Dynamin 2 Myopathy Mice, But Power Lags Behind
Genetic and pharmacological inhibition of myostatin restored muscle mass in a mouse model of dynamin 2-related centronuclear myopathy, though drug-induced ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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