Succulent Plant Extract Shows Promise Against Alzheimer’s in Fruit Fly Model
A methanol extract of the West African medicinal plant Caralluma dalzielii improved survival, behaviour, antioxidant defences, and tau-related gene expression ...
Tag: acetylcholinesterase
Butterfly-Shaped Coumarin Molecules Show Promise as Dual Alzheimer’s Enzyme Blockers
New halogenated bis-coumarin compounds inhibit both acetylcholinesterase and monoamine oxidase-B at micromolar concentrations, offering a dual-target template for Alzheimer's drug ...
Plant Compound Andrograpanin Outperforms Insecticide Temephos in Mosquito Enzyme Docking Study
A molecular docking study finds that andrograpanin, a diterpenoid from Andrographis paniculata, binds mosquito acetylcholinesterase more favorably than the standard ...
Computers Take On Crop Pests: How Molecular Docking Is Reshaping Insecticide Discovery
A comprehensive review in Results in Chemistry details how molecular docking, virtual screening, and ADMET prediction are accelerating the discovery ...
Pesticide Exposure in Pregnancy Linked to Early Infant Development Delays in Tanzania
A Tanzanian study of 337 mother–child pairs found that high first-trimester inhibition of maternal acetylcholinesterase, a marker of organophosphate pesticide ...
Common Medicinal Plant Shows Promise Against Cobra Venom in New Study
A hydromethanolic extract of Plumbago zeylanica aerial parts inhibited key cobra venom enzymes, prolonged survival in envenomated mice and showed ...
Computational Hunt Finds Candidate Molecule Striking Two Key Alzheimer’s Enzymes at Once
A computational screening pipeline identified compound H34 as a promising dual inhibitor of acetylcholinesterase and monoacylglycerol lipase for Alzheimer's disease ...
Aloe Vera Sugar Molecule Shows Promise Against Memory Loss in Rat Study
New research shows that acemannan, a sugar molecule from Aloe vera, reversed scopolamine-induced memory impairment in rats by restoring cholinergic, ...
Sodium Fluoride Disrupts Brain Chemistry and Behavior in Rats
A new rat study shows that prolonged sodium fluoride exposure at environmentally relevant doses drives oxidative stress, cholinergic disruption, astrocyte ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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