New Spatial Genomics Method SpaceA Reveals 3D Genome Architecture in Mouse Embryos
A new spatial 3D genomics technology called SpaceA maps long-range chromatin interactions inside intact mouse embryo tissue and uncovers a ...
Tag: 3D genome
Ancient DNA Reorganization May Explain How Octopuses Grew Such Complex Brains
A University of Vienna study finds that an ancient burst of genome reorganization created 3D DNA interactions, or regulatory entanglement, ...
How HPV Reshapes the 3D Genome to Lock Cervical Cancer Into Resistant States
A new review argues that host chromatin architecture and three-dimensional genome rewiring, not just HPV oncoproteins, stabilize malignant states and ...
Hidden Genome Folds Silence Two Tumor-Suppressing Genes in Aggressive Breast Cancer
Researchers have discovered that DNA methylation evicts the architectural protein CTCF from the HOXD locus, collapsing a chromatin loop that ...
Duck Genome Study Reveals Master Genetic Switch Behind Fat Deposition
A multi-omics study in ducks has uncovered a selected distal enhancer that remotely controls the ADM gene through SMAD2 recruitment, ...
Spatial Hi-C Maps 3D Genome Folding Directly Inside Brain Tissue
A new microfluidic method called spatial Hi-C maps genome-wide 3D chromatin folding directly within intact brain tissue sections, revealing lobule-specific ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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