About The Study: In this cross-sectional study, the expression of several stress-related genes in prostate tumors was higher among men residing in disadvantaged neighborhoods. This study is one of the first to suggest associations of neighborhood disadvantage with prostate tumor RNA expression. Additional research is needed in larger studies to replicate findings and further investigate interrelationships of neighborhood factors, tumor biology, and aggressive prostate cancer to inform interventions to reduce disparities.
About The Study: In this cross-sectional study, the expression of several stress-related genes in prostate tumors was higher among men residing in disadvantaged neighborhoods. This study is one of the first to suggest associations of neighborhood disadvantage with prostate tumor RNA expression. Additional research is needed in larger studies to replicate findings and further investigate interrelationships of neighborhood factors, tumor biology, and aggressive prostate cancer to inform interventions to reduce disparities.
Corresponding Author: To contact the corresponding author, Kathryn Hughes Barry, Ph.D., M.P.H., email kbarry@som.umaryland.edu.
To access the embargoed study: Visit our For The Media website at this link
(doi:10.1001/jamanetworkopen.2024.21903)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
Journal
JAMA Network Open
Cite Scienmag News
Nathaniel Bowman. (July 12, 2024). Neighborhood disadvantage and prostate tumor RNA expression of stress-related genes. Scienmag. https://scienmag.com/neighborhood-disadvantage-and-prostate-tumor-rna-expression-of-stress-related-genes/
Nathaniel Bowman. "Neighborhood disadvantage and prostate tumor RNA expression of stress-related genes." Scienmag, 12 July 2024, https://scienmag.com/neighborhood-disadvantage-and-prostate-tumor-rna-expression-of-stress-related-genes/. Accessed 4 September 2026.
Nathaniel Bowman. "Neighborhood disadvantage and prostate tumor RNA expression of stress-related genes." Scienmag. July 12, 2024. https://scienmag.com/neighborhood-disadvantage-and-prostate-tumor-rna-expression-of-stress-related-genes/
