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Nanopore sequencing identifies parent-of-origin specific age-associated methylation changes at imprinted loci in the human genome

July 29, 2026
in Medicine
Juliet Wilcox
By Juliet Wilcox Scienmag Editorial Profile - Human Genetics
Reading Time: 1 min read
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Nanopore sequencing identifies parent-of-origin specific age-associated methylation changes at imprinted loci in the human genome

Nanopore sequencing identifies parent-of-origin specific age-associated methylation changes at imprinted loci in the human genome

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Sigurpalsdottir, B., Holley, G., Sverrisson, S.Þ. et al. Nanopore sequencing identifies parent-of-origin specific age-associated methylation changes at imprinted loci in the human genome.
Nat Commun (2026).

Subject of Research: Medicine

Article Title: Nanopore sequencing identifies parent-of-origin specific age-associated methylation changes at imprinted loci in the human genome

Article References: Sigurpalsdottir, B., Holley, G., Sverrisson, S. Þ., Magnusdottir, D. N., Olafsson, P. I., Gylfason, A., Magnusson, O. Þ., Masson, G., Stefansson, O. A., & Halldorsson, B. V. (2026). Nanopore sequencing identifies parent-of-origin specific age-associated methylation changes at imprinted loci in the human genome. Nature Communications, 17(1), Article 9210. https://doi.org/10.1038/s41467-026-76240-w

Image Credits: AI Generated

DOI: 10.1038/s41467-026-76240-w

Keywords: age-associated epigenetic modifications, age-related epigenetic changes, allele-specific methylation, DNA methylation analysis, epigenetic aging biomarkers, genome imprinting, high-resolution methylation detection, human genome methylation patterns, imprinted loci in human genome, long-read sequencing in epigenetics, nanopore sequencing, parent-of-origin methylation

Cite Scienmag News

Juliet Wilcox. (July 29, 2026). Nanopore sequencing identifies parent-of-origin specific age-associated methylation changes at imprinted loci in the human genome. Scienmag. https://scienmag.com/nanopore-sequencing-identifies-parent-of-origin-specific-age-associated-methylation-changes-at-imprinted-loci-in-the-human-genome/

Juliet Wilcox. "Nanopore sequencing identifies parent-of-origin specific age-associated methylation changes at imprinted loci in the human genome." Scienmag, 29 July 2026, https://scienmag.com/nanopore-sequencing-identifies-parent-of-origin-specific-age-associated-methylation-changes-at-imprinted-loci-in-the-human-genome/. Accessed 4 September 2026.

Juliet Wilcox. "Nanopore sequencing identifies parent-of-origin specific age-associated methylation changes at imprinted loci in the human genome." Scienmag. July 29, 2026. https://scienmag.com/nanopore-sequencing-identifies-parent-of-origin-specific-age-associated-methylation-changes-at-imprinted-loci-in-the-human-genome/

Tags: age-associated epigenetic modificationsage-related epigenetic changesallele-specific methylationDNA methylation analysisepigenetic aging biomarkersgenome imprintinghigh-resolution methylation detectionhuman genome methylation patternsimprinted loci in human genomelong-read sequencing in epigeneticsnanopore sequencingparent-of-origin methylation
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