George Mason University becomes new home for 400,000 biological specimens from Inova Health Systems

George Mason University’s College of Public Health is the new home of 400,000 biological specimens through a partnership with Inova Health Systems. This repository of specimens, called a biobank, is an extensive collection of obstetrical and perinatal samples, along with follow-up health information, providing a rare and invaluable asset in public health and in the education of our future health, science, and technology care workforce.

“The biorepository creates opportunities for Mason to expand its collaborations with Inova, biotechnology partners, and other universities in Virginia, as well as unique educational opportunities,” said Melissa Perry, dean of the college. 

Larry Maxwell, president of the Women’s Service Line at Inova Health System, said, “The investment by Inova Health System as well as additional support from the Fairfax County Government have created an unprecedented resource of placenta as well as blood specimens from mother, father, and baby [trios] corresponding to over 4,000 families. These biospecimens and corresponding data continue to support scientific research to better understand the obstetrical diseases that contribute to rising rates of maternal morbidity and mortality locally, regionally, and nationally.” 

A range of specimens (e.g., saliva, urine, and blood) were collected with consent from an Inova cohort study that followed more than 4,000 women, their partners, and their children from pregnancy into early childhood to examine maternal health, pregnancy outcomes, and children’s growth and development. 

“The transfer of the biobank from Inova Health System to the College of Public Health serves as a testament to our strong public–private partnership, and underscores George Mason’s dedication to advancing health in pregnancy and early childhood,” said Alison Cuellar, College of Public Health associate dean for research. The biobank is housed at the university’s Science and Technology Campus in Manassas, Virginia. 

The biobank offers an unprecedented opportunity for George Mason researchers to engage with and involve Virginia’s undergraduate and graduate students in health and public health science, to expand Virginia’s health, science, and technology workforce pipeline and enhance its diversity.  

“The availability of such comprehensive and diverse datasets within a single biobank is rare, making it an attractive asset for collaboration and groundbreaking research endeavors,” said Michael S. Bloom, program lead of the College of Public Health Biobank and George Mason professor.  

Bloom and co-lead Carolyn Drews-Botsch started the work for the biobank transfer in 2021. Inova chose Bloom and Drews-Botsch after extensive vetting of their prior research experience, including involvement in large cohort studies, such as those from which these specimens are drawn. Space at the SciTech Campus for the biobank was renovated to hold the 11 tanks (called dewars) and freezers full of specimens. The containers are kept between -80 degrees C and -190 degrees C to maintain specimen integrity during long-term storage. 

“These specimens will be vital for public health researchers who are looking to identify associations and factors that support healthy pregnancy and child health and ultimately benefit the public’s health,” said Drews-Botsch, a professor in the College of Public Health. 

The professors expect the biobank to become a leading resource for collaborative projects once a research database is developed, with other researchers analyzing the data to answer important public health questions. 

“By actively fostering these partnerships, George Mason can position itself as a leader in research around maternal health and early childhood and contribute to the advancement of public health on a larger scale,” Perry said.