Cancer
Interleukin-2 emerges as both engine and saboteur in tumor-infiltrating lymphocyte therapy
A new review details how interleukin-2 both powers and undermines tumor-infiltrating lymphocyte therapy, and how engineered alternatives may finally break...
Liposomal Paclitaxel With HER-2 Blockers Shows Strong Real-World Results in Advanced Breast Cancer
A real-world study of 526 patients found that paclitaxel liposome combined with anti-HER-2 targeted therapies delivered median overall survival of...
Immune Cells Inside Breast Tumours May Signal Spread to Lymph Nodes
A Malaysian study of 241 early breast cancer patients finds that higher levels of tumour-infiltrating lymphocytes are linked to lower...
Tea Bags, Reminder Cards and Texts Boost Survey Responses in Breast Cancer Trial
A mixed-methods study embedded in the FASTRACS randomized controlled trial found that personalized reminders, printed questionnaires and phone-based completion, co-designed...
Rare Hip Tumor Masquerading as Infection Diagnosed Through Imaging and Pathology
A rare diffuse-type tenosynovial giant cell tumor eroding the hip socket was unmasked only after surgery and microscopic analysis, highlighting...
Iron and Methionine Metabolism Drive Fat Browning in Cancer Cachexia
A new Nature Cancer study identifies an iron-regulated methionine oxidation pathway and the repair enzyme MSRA as drivers of adipose...
Common drugs, sweeteners and pesticides can act as antibiotics on gut bacteria
A new review warns that common non-antibiotic drugs, food additives and environmental chemicals exert antimicrobial effects that reshape the human...
RNA Editing Enzyme ADAR1 Emerges as Key Switch That Turns Cold Bladder Tumors Hot
Researchers found that inhibiting the RNA editing enzyme ADAR1 reprograms the immunosuppressive tumor microenvironment of bladder cancer and sensitizes it...
Scientists Reverse Radiotherapy Resistance in Lung Cancer by Rewiring the Immune Microenvironment
New research shows that lung tumors become radioresistant through ATR signaling activation and immune suppression, but innate immune agonists and...
Pregnancy and Breastfeeding Leave Lasting Marks on Breast Tissue Stroma
A new study links reproductive history, including parity, age at first pregnancy, and breastfeeding, to distinct stromal marker expression patterns...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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