Biology
Cellular Scissors: How the Deubiquitinase STAMBPL1 Shapes Health and Fuels Cancer
A new review details how the JAMM-family deubiquitinase STAMBPL1 maintains cellular homeostasis and, when overexpressed, drives tumor progression, metastasis, and...
Machine learning method dicast spots disease-causing DNA deletions short-read tools miss
A machine learning method called dicast, trained on a manually curated multi-technology ground truth, detects structural variants from short-read sequencing...
Waste Wool and Graphene Oxide Combine to Supercharge an Extremophile Enzyme
Researchers at Xiamen University have built a sandwich-like biomaterial from waste wool keratin and graphene oxide that immobilizes an extremophile...
Fungi Ferment a Greener Route to Critical Metals from Electronic Waste
Researchers have engineered a fed-batch fungal fermentation process that produces oxalic acid at scale as a sustainable leaching agent for...
Genetic Study Reveals How Ethiopia’s Abergelle Goats Could Grow Faster Through Smarter Breeding
A six-year genetic study of nearly 2,000 Abergelle goats in Ethiopian community breeding programmes finds moderate heritability for growth traits...
Bacterial urease genomes reveal conserved architecture and ancient gene-swapping clues
A comparative analysis of 237 bacterial genomes shows that the urease system is architecturally conserved yet evolutionarily flexible, with evidence...
Epigenetic Boost Fails to Awaken Immune Therapy in Bile Duct Cancer Trial
A phase 2 trial found that the HDAC inhibitor entinostat combined with nivolumab produced no tumor responses in advanced cholangiocarcinoma,...
Enzyme GDH1 Keeps Breast Cancer Persister Cells Alive During Chemotherapy
New research shows that the mitochondrial enzyme GDH1 sustains drug-tolerant persister cells in triple-negative breast cancer by coordinating glutamine metabolism,...
PTPN6 Gene Emerges as Potential Prognostic Marker in Bladder Cancer
A new bioinformatics study links PTPN6 overexpression and promoter hypomethylation to overall survival in bladder cancer, positioning the gene as...
Why the Creamiest-Tasting Milk Isn’t Always the One You’d Expect
A new study of eight commercial UHT milk products shows that consumer liking depends on an integrated quality system of...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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