Biology
Gut Microbe’s Stress-Linked Metabolite Drives Breast Cancer Spread, and an Ancient Drug Blocks It
New research traces how chronic stress fuels breast cancer metastasis through a gut bacterium's tryptophan metabolite and shows that the...
Computational Vaccine Design Targets Toxoplasma’s Dense Granule Arsenal
Researchers have computationally designed a multi-epitope vaccine candidate against Toxoplasma gondii built from six dense granule antigens, with the lead...
Nanopore Pipeline Delivers Sanger-Level Accuracy for Detecting Kidney Disease Gene Variants
Chilean researchers have developed and clinically validated a nine-stage Oxford Nanopore bioinformatic pipeline that detects PKD1 variants with complete Sanger...
Boron-Based Compounds Show Potent Larvicidal Power Against Disease-Carrying Mosquitoes
Newly synthesized diborane derivatives kill Aedes aegypti, Aedes albopictus, and Culex pipiens larvae at low concentrations by severely damaging the...
Male Bears Rebuilt Hokkaido’s Brown Bear Population After an Ice Age Collapse
Genomic analysis of Hokkaido's brown bears reveals that male-biased dispersal drove the population's post-glacial recovery, homogenizing the Y chromosome and...
Genes Behind Pregnancy Inflammation Show Only Weak Ties to Gestational Diabetes
A genome-wide study of early-pregnancy C-reactive protein in the nuMoM2b cohort maps known and new CRP loci but finds only...
Aging Cells Ratchet Up a Gene Called EYA4, and Silencing It Delays Senescence
New research shows that the age-upregulated gene EYA4 drives cellular senescence by partnering with the transcription factor SIX2 to boost...
Machine learning finds scent compounds that steer honey bees away from pesticides
UC Riverside researchers used machine learning to screen more than 50 million compounds and identify odorants that safely repel honey...
KNOT: A Knockoff-Powered Neural Network Hunts Hidden Autism Risk Genes
A new knockoff-augmented neural network called KNOT brings false discovery rate control to deep-learning-based genetic association studies, uncovering more autism...
Sunflower Genes Could Hold the Key to Climate-Proof Crops in the World’s Driest Farmlands
A new review argues that sunflower's remarkable tolerance to combined drought, heat, salt, and pathogen stress makes it a powerful...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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