Biology
Engineered Protein Breakdown Supercharges Drug-Free Selection of High-Producing CHO Cells
Researchers at Inha University engineered destabilized glutamine synthetase variants that dramatically increase selection stringency in CHO cells, enabling drug-free isolation...
Common Bacterium Found Widespread in Italian Sand Flies Could Aid Disease Control
A three-year survey of sand flies in Northern Italy found that nearly 40 percent carry a single Wolbachia Supergroup B...
Milk Protein Gene CSN3 Emerges as a Driver of Colorectal Cancer Growth Through AKT Signaling
New research shows that the milk protein gene CSN3 is elevated in colorectal cancer and drives tumor growth, invasion, and...
Citrus Flavonoid Meets Nuclear Medicine in Twin Radiometal Design for Breast Cancer
Computational simulations show that the citrus flavonoid hesperidin can be paired with technetium for imaging and rhenium for therapy, with...
Sea Cucumber Immune Cells Revealed in Unprecedented Detail by Single-Cell Sequencing
A single-cell RNA sequencing study of the sea cucumber Holothuria forskali has identified ten distinct coelomocyte populations, including a clearly...
Elm Cultivar Genomes Decoded: Chloroplast DNA Reveals Hidden Fingerprints for Authentication
Scientists have sequenced the complete chloroplast genomes of five Ulmus pumila cultivars, uncovering hypervariable DNA regions that can finally distinguish...
AI Reads the Genome Like Language to Uncover Hidden Gene Interactions
A new deep learning framework called Epiformer combines the Evo 2 genome language model with a dual-channel network to detect...
Trapping Lactic Acid Bacteria in Smart Carriers Could Transform Food Biotech
A new review in Food Science and Biotechnology details how encapsulating lactic acid bacteria in engineered carrier materials boosts their...
Two Rival Gene Networks Decide Whether B Cells Become Antibody Factories or Memory Makers
Single-cell mapping of human B cell activation reveals that memory cells are intrinsically biased toward becoming plasma cells while naive...
Synthetic Plant Immune Receptors Designed on Computers and Evolved in Living Plants
Researchers are combining computational de novo protein design with directed evolution in plants to create synthetic immune receptors that can...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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