Biology

A two-stage culture system expanded mouse hepatocytes and produced organoids with partial recovery of hepatic metabolism, zonation-related responses and urea...

A computational framework linked spatial gene-expression gradients to net-production direction under steady-state and positive-flow assumptions, with reproducible directions in human...

An engineered gibberellin and receptor system showed that full Arabidopsis root elongation requires coordinated signalling in the endodermis and epidermis.

A controlled infection study links late induction of the banana susceptibility gene MusaDMR6 to Fusarium wilt progression in the commercially...

A seasonal field study in Bangladesh found that Black-tailed godwits selected benthic prey and also consumed rice and uri grass...

A hierarchical deep latent-variable model outperformed existing methods at identifying causal triggers and predicting perturbation responses in synthetic and real...

A multiomic study of Mycoplasma hyorhinis SK76 links specific methyltransferases to genome-wide DNA methylation patterns but does not directly test...

Keratin 9 restrains mechanical YAP1 signalling in palmoplantar skin, and experimental YAP1 inhibition reduced thickened epidermis in keratin 9-deficient mice.

A focused review finds that cGAS–STING and AIM2 claims in atherosclerosis depend on the DNA source, cellular lineage, disease stage...

Coral-associated Endozoicomonas bacteria synthesize testosterone and progesterone, while laboratory exposure to the hormones transiently alters coral immune-gene expression during heat...