Biology

In the deserts and dry forests of Mexico, the lesser long-nosed bat, Leptonycteris yerbabuenae, undertakes one of the most remarkable...

Researchers have developed a computational framework that integrates time-series single-cell RNA sequencing with spatial transcriptomics to reconstruct spatiotemporal cell-type redistribution...

A new review argues that CRISPR-based DNA methylation editing can transform cancer epigenetics from a correlative science into a causal...

A small domain of the cofactor Ufd1 unfolds K48-linked ubiquitin without ATP by cooperatively binding two ubiquitin molecules, providing the...

Scientists have engineered FenixS and Ash1, a compact biliverdin-binding protein pair whose binding affinity rises more than 1,200-fold under far-red...

Researchers have identified ANKRD11 as a chromatin regulator whose loss reprograms CD8+ T cells to fight chronic hepatitis B and...

New research shows that cancer therapy selects for preexisting drug-resistant and druggable mutant clones in normal esophageal tissue, reshaping the...

A large-scale forest experiment reveals that tree species richness and mycorrhizal fungal dominance independently shape biodiversity across food webs, with...

Suppressor screens in worms, human cells and mouse oocytes reveal tubulin variants that can counteract disease-causing tubulin mutations and restore...

In the world of behavioral science, few findings have proven as robust—or as puzzling—as the suboptimal choice phenomenon. When pigeons...