Medicine
Extracorporeal Ozone Shows Early Promise Against Experimental Gram-Negative Sepsis in Pigs
An exploratory pig study found that one hour of extracorporeal ozone treatment lowered organ-failure scores and preserved blood pressure in...
Exon-Skipping Splicing Changes Distinguish Alzheimer’s Disease from Progressive Supranuclear Palsy
A genomic study of temporal cortex tissue identifies hundreds of exon-skipping events that separate Alzheimer's disease from progressive supranuclear palsy,...
Maternal BMI Shows No Clear Link to Pregnancy Cholestasis, Review Finds
A scoping review of twenty studies finds no consistent association between maternal BMI and intrahepatic cholestasis of pregnancy, while lower...
Novel CSNK2B Mutation Sheds Light on Epilepsy Severity in Rare Syndrome
A newly identified CSNK2B mutation in a Chinese family with early-onset seizures joins an analysis of 103 cases suggesting protein-level...
Green Solvents Offer Safer Replacements for Chemistry’s Most Hazardous Liquids
A new review maps proven green replacements for hazardous solvents including pyridine, toluene, THF, DMF and carbon tetrachloride across major...
CD4 T Cell Help Powers Immunotherapy Response in Tumors Lacking MHC-I
Mouse experiments show that CD4+ T cells license CD8+ T cells through CD40 signaling, enabling combination immunotherapy to eliminate mismatch...
Culture Medium Rewrites Drug Sensitivity in Patient-Derived Tumor Organoids
A new study shows that the choice between Wnt-based and OncoPro culture medium reshapes the transcriptional state and drug sensitivity...
Tumor acidity emerges as a metabolic barrier blocking cancer immunotherapy
A narrative review argues that the acidic tumor microenvironment suppresses antitumor immunity and that targeting acidity is a preclinically supported...
Aneurysm location alone fails to predict need for multiple clips in MCA surgery
A retrospective single-center cohort of 86 middle cerebral artery aneurysm operations found that segmental location did not independently predict multiple-clip...
AI in cataract care stays stuck at internal testing, scoping review finds
A systematic scoping review of 185 studies finds most cataract AI tools have only undergone internal validation, and no clinically...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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