CLDN4 Expression Causally Increases Ovarian Cancer Risk in Multi-Omics Study
A multi-omics study identified CLDN4 expression as causally linked to ovarian cancer risk and highlighted it as a promising therapeutic ...
Tag: WGCNA
Opium Poppy Metabolism Shifts Significantly Across Organs and Seed Developmental Stages
Integrated transcriptomic and untargeted metabolomic analyses in opium poppy demonstrate that specialized metabolism is strongly partitioned by organ type and ...
Fluctuating Coastal Oxygen Regimes Drive Rapid Shifts in Sediment Microbial Activity
A Baltic Sea field investigation reveals that coastal sediments subject to fluctuating oxygen conditions undergo pronounced shifts in microbial composition ...
Computational Analysis Links Diethyl Phthalate to Potential Rheumatoid Arthritis Pathways
A computational study combining machine learning and molecular docking has identified candidate targets and pathways potentially connecting diethyl phthalate exposure ...
Moth Gene Variant Links Elevation to Thermal Tolerance
A study in Ecology and Evolution identifies an HSP60A gene variant in the moth Thitarodes xiaojinensis that links elevational adaptation ...
Cross-Disease Transcriptomic Analysis Links Tic Disorders and Allergic Diseases via GPX7
A cross-disease transcriptomic study and mouse model demonstrate that allergic sensitization exacerbates tic-like stereotypies alongside reduced GPX7 expression and heightened ...
ETS2 Transcription Factor Drives Chemoimmunotherapy Resistance in Esophageal Squamous Cell Carcinoma
A single-cell RNA sequencing study reveals that an ETS2-expressing epithelial cell subpopulation promotes neoadjuvant chemoimmunotherapy resistance in esophageal squamous cell ...
Three-Gene Kinic Biomarker Panel Reaches 0.952 Diagnostic Accuracy in Cervical Cancer
An integrated transcriptomic and single-cell study identified CDKN2A, XPO1, and TST as a three-gene kinic-related diagnostic panel achieving an AUC ...
Silencing HSP90AB1 Inhibits Hepatocellular Carcinoma Cells by Promoting R-Loop Accumulation
Researchers identified HSP90AB1 as an up-regulated gene in hepatocellular carcinoma whose silencing promoted R-loop accumulation and suppressed cancer cell viability, ...
Elevated OIP5 Expression Drives Malignant Progression in Lung Adenocarcinoma Cells
A multi-omics and in vitro validation study demonstrates that elevated OIP5 expression drives cell cycle progression and promotes lung adenocarcinoma ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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