NIH-funded study probes prenatal vaping and offspring antiviral immunity
A five-year NIH-funded Wayne State study will use preclinical models to investigate how e-cigarette components during pregnancy affect fetal lung ...
Tag: Type I interferon
Silent Interferon Signals May Flag Ovarian Tumors That Shrug Off Chemotherapy
A cautious reanalysis of single-cell, TCGA, MRI, and cell-line data links muted type-I interferon signaling and altered cell-state programs to ...
Lupus quietly doubles heart attack risk, and Framingham scores keep missing it
A new review maps why conventional heart risk scores underestimate danger in lupus and which therapies may help.
How Ancient Chinese Medicine Compounds Rewire the Brain’s DNA Alarm System
A new review maps how traditional Chinese medicine compounds, herbal formulas, and electroacupuncture modulate the cGAS-STING neuroimmune pathway, revealing that ...
How a Single Transcription Factor Decides Whether Sunburned Skin Cells Live or Die
New research shows that the transcription factor C/EBPβ normally restrains an inflammatory interferon and TNF-α program that, when unleashed in ...
Cellular RNA Sensors Form First Line of Defense Against Neglected Mosquito-Borne Virus
New research identifies the RIG-I, MDA5, MAVS, and IRF3 signaling axis as the primary pathway by which human cells detect ...
Lost Genetic Brakes Push Immune Cells Into an Interferon State Seen in Eczema Patients
Researchers in Tokyo engineered a tracking system for Foxp3-deficient regulatory T cells and found that combined loss of Foxp3 and ...
Alzheimer’s Risk Gene BIN1 Acts as a Brake on Brain Inflammation
New research shows that the Alzheimer's risk gene BIN1 acts as a brake on microglial inflammation, and its loss exaggerates ...
Antiviral Protein IFIT1 Emerges as a Driver of Lupus Progression
New research shows that the antiviral protein IFIT1 is elevated in immune cells of lupus patients, where it promotes cell ...
Scientists Propose Framework to Test Whether Oropouche Virus Harms Fetuses
Researchers propose a combined experimental and epidemiological framework to determine whether Oropouche virus can cause vertical transmission and adverse fetal ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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