Tag: tumour microenvironment

A new review in Nature Reviews Clinical Oncology details how the tumour extracellular matrix, or matrisome, drives cancer progression and ...

Researchers at Trinity College Dublin report that KHYG-1 natural killer cells retain their cancer-killing function after exposure to the tumour ...

A review in Experimental & Molecular Medicine examines how chronic antigen exposure and a hostile tumour microenvironment reprogram T cells ...

An armoured GPC3-targeted CAR T cell therapy engineered to resist TGFβ-mediated immunosuppression showed promising initial results in 36 patients with ...

A new review maps how secreted protein circuits in gastrointestinal tumours govern immune recruitment, suppression and response to checkpoint immunotherapy.

A new review in Molecular Cancer details how five classes of nanomaterials could breach the blood–brain barrier and dismantle the ...

A new review maps the laboratory models—from organoids to humanised mice to computational pipelines—that could finally bring personalised treatment to ...

A major new review shows that long non-coding RNAs orchestrate the colorectal cancer tumour microenvironment, offering new biomarkers and therapeutic ...

Researchers are using PD-L1-targeted PET/CT imaging to directly visualise whether the immunotherapy drug atezolizumab saturates its target in tumours, offering ...

A new review argues that matrix-bound extracellular vesicles retained within the extracellular matrix form a distinct, tissue-specific signalling population with ...