One Cancer Gene, Two Fates: Study Shows Senescent Cells Split Into Tumor Blockers and Tumor Seeds
An NYU Abu Dhabi study in EMBO Reports shows that a single cancer-causing gene drives liver cells into distinct senescent ...
Tag: tumor suppression
Gallic Acid Shrinks Tumors in Mice While Sparing Blood Cells, Study Finds
A new preclinical study shows that orally delivered gallic acid significantly inhibited sarcoma tumor growth in mice by suppressing proliferation, ...
Hidden p53 Variant Δ246p53 Emerges as a DNA Damage Sentinel Driving Cellular Senescence
Researchers have discovered Δ246p53, a conserved 18-kilodalton p53 isoform translated from codon 246 that responds to DNA damage and enhances ...
Fruit Fly Protein Xrp1 Guards the Genome Through Two Separate Tumor-Suppressing Pathways
A new PLOS Genetics study shows that the Drosophila protein Xrp1 protects genome integrity through both a p53-dependent DNA damage ...
Tiny RNA Molecule Triggers Explosive Cell Death in Aggressive Breast Cancer
Researchers have discovered that the microRNA miR-205-3p triggers inflammatory pyroptotic cell death in triple-negative breast cancer by repressing HSP90AB1, while ...
MYSM1 halts cervical cancer growth by activating ITPR1-driven autophagy
Cervical cancer remains one of the most preventable yet persistent malignancies worldwide, and every new insight into its molecular machinery ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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