Two BCL-2 Gene Variants Linked to Protein Levels and Aggressive Bladder Cancer
Brazilian researchers have found that a BCL-2 promoter variant influences protein expression in bladder tumors while a specific haplotype triples ...
Tag: tumor recurrence
TRK Protein Staining in Childhood Rhabdomyosarcoma Flags Aggressive Tumors but Misses the Gene Fusions That Matter
A Hungarian study of 45 pediatric rhabdomyosarcoma cases found TRK protein expression in 38 percent of tumors—concentrated in the aggressive ...
Hidden Tumor Spread: Mapping Biopsies Guide Surgery for Recurrent Skin Cancer
A recurrent basal cell carcinoma case from Japan reveals how deep subcutaneous tumor growth and superficial lateral microextension can evade ...
Brain Scans Miss Hidden Tumor Spread, Landmark Glioma Imaging Trial Reveals
A prospective Canadian pilot study found that FET-PET/MRI revealed significantly larger metabolically active tumor volumes than conventional MRI in more ...
Recurring Brain Tumors Follow Distinct Genetic Paths, Global Study Finds
An international study of 183 patients reveals that IDH-mutant gliomas follow divergent genetic evolutionary paths at recurrence, with oligodendrogliomas acquiring ...
Radioactive Tiles Implanted During Surgery Halve Recurrence Risk in Brain Metastases Trial
A Phase 3 trial found that cesium-131 collagen tiles implanted during brain metastasis surgery reduced one-year recurrence to 1.3 percent ...
Experimental Drug SMIP004 Hunts Down Dormant Cancer Cells Left Behind by Chemotherapy
Researchers report that the mitochondria-targeting compound SMIP004 selectively kills therapy-induced senescent cancer cells by promoting degradation of the AMPK-stabilized metabolic ...
How Tumors Survive Radiation: Plastic Cells and Tolerant Niches Drive Recurrence
A new review in Molecular Cancer reframes radioresistance as an ecosystem-level phenomenon in which plastic residual tumor cells survive radiation ...
Measuring Swelling Around Treated Brain Tumors May Reveal Why Some Fail Radiation Therapy
A Yale-led study of 36 patients shows that tracking volumetric changes in perilesional FLAIR hyperintensity after Gamma Knife radiosurgery can ...
Single Gene Mutation Reveals Why Throat Cancers Come Back After Cisplatin Success
A new study shows that mutations emerging in the ENPP1 gene during treatment drive cisplatin resistance and recurrence in hypopharyngeal ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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