Engineered NK Cells Target CD73 to Attack Hard-to-Treat Lung Adenocarcinoma
Preclinical research shows that natural killer cells engineered with a CD73-targeting receptor kill relapsed or refractory lung adenocarcinoma cells in ...
Tag: tumor microenvironment
Tumor cells may revert to stem-like states, review argues
A new review proposes that mature tumor cells can dedifferentiate into cancer stem cells, acting as a non-genetic engine of ...
Tumor Blood Vessels Act as an Immune-Regulatory Hub, Review Proposes
A review in Cellular Oncology proposes that tumor blood vessels actively regulate antitumor immunity through angiocrine, metabolic and structural mechanisms.
Gut Microbe Metabolites Engineered as Programmable Drugs Against Cancer
A new review argues that gut bacterial metabolites such as butyrate and indoles can be engineered as programmable drugs to ...
Immune Cells That Sabotage Treatment: Th17 Signals Help Cervical Cancer Cells Survive Therapy
A laboratory study finds that Th17-derived IL-17 signaling activates AKT in cervical carcinoma cell lines, reducing their sensitivity to cisplatin, ...
Serine Supplements Boost T Cell Attack on Tumors in Preclinical Models
Preclinical research shows serine supplementation, rather than restriction, suppresses tumor growth and reinvigorates CD8+ T cells by countering tumor cell ...
Cationic Lipid Nanoparticles Emerge as Versatile Delivery Platforms for Cancer Therapy
A new review examines how cationic lipid-based nanoparticles carry RNA, proteins and peptides into cancer cells, and why clinical translation ...
Nanomedicine Aims to Sharpen Colorectal Cancer Diagnosis and Treatment
A new open-access review in Cancer Nanotechnology surveys how nanomaterials could improve colorectal cancer diagnosis, targeted therapy, and personalized theranostics.
AI in Triple Negative Breast Cancer Research Surges, Ten-Year Mapping Shows
A ten-year bibliometric analysis of 320 articles finds artificial intelligence research on triple negative breast cancer peaked at 104 publications ...
Caloric Restriction Makes Colorectal Tumors More Vulnerable to Radiation in Mice
In a mouse and cell study, caloric restriction and fasting enhanced radiation's tumor-killing effects through the cGAS-STING pathway while protecting ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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